Previous Publications
2008
Peisker, K., Braun, D., Wölfle, T., Hentschel, J., Fünfschilling, U., Fischer, G., Sickmann, A., and Rospert, S. (2008). Ribosome-associated complex binds to ribosomes in close proximity of Rpl31 at the platform surrounding the exit of the polypeptide tunnel in yeast. Mol Biol Cell 19, 5279-5288.
2007
Conz, C., Otto, H., Peisker, K., Gautschi, M., Wolfle, T., Mayer, M. P., and Rospert, S. (2007). Functional characterization of the atypical Hsp70 subunit of yeast ribosome-associated complex. J. Biol. Chem. 282, 33977-33984.
Raue, U., Oellerer, S., and Rospert, S. (2007). Association of protein biogenesis factors at the yeast ribosomal tunnel exit is affected by the translational status and nascent polypeptide sequence. J. Biol. Chem. doi:10.1074/jbc.M611436200.
2006
Rospert, S., and Chacinska, A. (2006). Distinct yet linked: chaperone networks in the eukaryotic cytosol. Genome Biol. 7, 208.
2005
Rospert, S., Rakwalska, M. and Dubaquié, Y. (2005) Polypeptide chain termination and stop codon readthrough on eukaryotic ribosomes. Rev. Physiol. Biochem. Pharmacol., 155, 1-30.
Otto, H., Conz, C., Maier, P., Wölfle, T., Suzuki, C.K., Jenö, P., Rücknagel, P., Stahl, J., and Rospert, S. (2005) The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex (mRAC). Proc. Natl. Acad. Sci. USA, 102, 10064-10069.
Huang, P., Gautschi, M., Walter, W., Rospert, S., and Craig, E.A. (2005) The Hsp70 Ssz1 modulates the function of the ribosome-asscoiated J-protein Zuo1. Nat. Struct. Mol. Biol., 12, 497-504.
Rospert, S., Gautschi, M., Rakwalska, M. and Raue, U. (2005) Ribosome-bound proteins acting on newly synthesized polypeptide chains. In Buchner, J. and Kiefhaber, T. (eds.), Protein Folding Handbook. Wiley-VCH, Vol. II., 429-458.
2004
Rakwalska M, Rospert, S (2004) The Ribosome-Bound Chaperones RAC and Ssb1/2p Are Required for Accurate Translation in Saccharomyces cerevisiae. Mol Cell Biol 24, 9186-97.
Rospert, S. (2004) Ribosome function: governing the fate of a nascent polypeptide. Curr. Biol. 14, R386-R388
2003
Gautschi, M., Just, S., Mun, A., Ross, S., Rücknagel, P., Dubaquié, Y., Ehrenhofer-Murray, A. and Rospert, S. (2003) The yeast Na-acetyltransferase NatA is anchored to the ribosome and interacts with nascent polypeptides. Mol. Cell. Biol., 23, 7403-7414.
Wiedemann, N., Kozjak, V., Chacinska, A., Schönfisch, B., Rospert, S., Ryan, M.T., Pfanner, N. and Meisinger, C. (2003) A machinery for protein sorting and assembly in the mitochondrial outer membrane. Nature, 424, 565-571.
2002
Rospert, S., Dubaquié, Y. and Gautschi, M. (2002) NAC - Nascent-polypeptide Associated Complex. Cell. Mol. Life Sci., 59 1632-1639.
Gautschi, M., Mun, A., Ross, S. and Rospert, S. (2002) A functional chaperone triad on the yeast ribosome. Proc. Natl. Acad. Sci. USA, 99, 4209-4214.
2001
Chaudhuri, T.K., Farr, G.W., Fenton, W.A., Rospert, S. and Horwich, A.L. (2001) GroEL/GroES-mediated folding of a protein too large to be encapsulated Cell, 107, 235-246.
Rospert, S. and Gautschi, M. (2001) Anstandsdamen für neusynthetisierte Proteine. Bioforum, 24, 500-518.
Gautschi, M., Lilie, H., Fünfschilling , U., Mun, A., Ross, S., Lithgow, T., Rücknagel, P. and Rospert, S. (2001) RAC, a stable ribosome-associated complex in yeast formed by the DnaK-DnaJ homologs Ssz1p and zuotin. Proc. Natl. Acad. Sci. USA 98, 3762-3767.
2000
Chacinska A., Boguta, M., Krzewska, J., and Rospert S. (2000) Prion-dependent switching between respiratory competence and deficiency in the yeast nam9-1 mutant. Mol. Cell. Biol 20, 7220-7229.
Dubaquié, Y., Looser, R., and Rospert, S. (2000) Purification of yeast mitochondrial hsp60. Meth. Mol. Biol. 140, 139-143.
1999
Fünfschilling, U. and Rospert, S. (1999) Nascent-polypeptide-associated complex stimulates protein import into yeast mitochondria. Mol. Biol. Cell 10, 3289-3299.
Braune, A., Bendrat, K., Rospert, S., and Buckel, W. (1999) The sodium ion translocating glutaconyl-CoA decarboxylase from Acidaminococcus fermentans: cloning and function of the genes forming a second operon. Mol. Microbiol. 31, 473-487.
selected previous publications (original papers)
Dubaquié, Y., Looser, R., Fünfschilling, U., Jenö, P., and Rospert, S. (1998) Identification of in vivo substrates of the yeast mitochondrial chaperonins reveals overlapping but non-identical requirement for hsp60 and hsp10.EMBO J.17, 5868-5876.
Komiya, T., Rospert, S., Koehler, C., Looser, R.,Schatz, G., and Mihara, K. (1998) Interaction of mitochondrial targeting signals with acidic receptor domains along the protein import pathway: Evidence for the "acid chain” hypothesis. EMBO J. 17, 3886-3898.
Dolinski, K., Scholz, C., Muir, R. S., Rospert, S. , Schmid, F. X., Cardenas, M. E., Heitmann, J. (1997) Functions of FKBP12 and mitochondrial cyclophilin active site residues in vitro and in vivo in Saccharomyces cerevisiae. Mol. Biol. Cell. 8, 2267-2280.
Dubaquié, Y., Looser, R., and Rospert, S. (1997) Significance of chaperonin 10-mediated inhibition of ATP hydrolysis by chaperonin 60. Proc. Natl. Acad. Sci. USA 94, 9011-9016.
Komiya, T., Rospert, S., Schatz, G., Mihara, K. (1997) Binding of mitochondrial precursor proteins to the cytoplasmic domains of the import receptors Tom70 and Tom20 is determined by cytoplasmic chaperones. EMBO J. 16, 4267-4275.
Horst, M., Oppliger, W., Rospert, S., Schönfeld, H.-J., Schatz, G. and Azem, A. (1997) Sequential action of two hsp70 complexes during protein import into mitochondria. EMBO J.16, 1842-1849.
Rospert, S., Looser, R., Dubaquié, Y., Matouschek, A., Glick, B. S. and Schatz, G. (1996) Hsp60-independent protein folding in the matrix of yeast mitochondria. EMBO J. 15, 764-774.
Matouschek, A., Rospert, S., Schmid, K., Glick, B. S. and Schatz, G. (1995) Cyclophilin catalyzes protein folding in yeast mitochondria. Proc. Natl. Acad. Sci. USA92, 6319-6323.
Haucke, V., Lithgow, T., Rospert, S., Hahne, K. and Schatz, G. (1995) The yeast mitochondrial protein import receptor Mas20p binds precursor proteins through electrostatic interaction with the positively charged presequence. J. Biol. Chem. 270, 5565-5570.
Rospert, S., Müller, S., Schatz, G. and Glick, B. S. (1994) Fusion proteins containing the cytochrome b2 presequence are sorted to the mitochondrial intermembrane space independently of hsp60. J. Biol. Chem. 269, 17279-17288.
Rospert, S., Glick, B. S., Jenö, P., Schatz, G., Todd, M. J., Lorimer, G. H. and Viitanen, P. V. (1993) Identification and functional analysis of chaperonin-10, the GroES Homolog from yeast mitochondria. Proc. Natl. Acad. Sci. USA90, 10967-10971.
Rospert, S., Junne, T., Glick, B. S. and Schatz, G. (1993) Cloning and disruption of the gene encoding yeast mitochondrial chaperonin 10, the homolog of E. coli GroES. FEBS Lett. 335, 358-360.