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Groups
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Prof. Dr. N. Pfanner
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(Executive Director Institute of Biochemistry & Molecular Biology and Director of Biochemistry I)
investigates the mechanisms of protein sorting and folding in the cell, in particular the targeting and assembly of mitochondrial proteins.
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Prof. Dr. S. Rospert
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(Director of Biochemistry II)
identifies and characterizes proteins associating with ribosoms and investigates their interactions with newly synthesized polypeptide chains.
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Prof. Dr. C. Hunte
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Structure, mechanism and function of membrane proteins involved in ion transport and cellular respiration and their interaction with signalling pathways
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Prof. Dr. H.-G. Koch
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investigates the insertion and assembly of membrane proteins and studies the cellular stress response.
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Prof. Dr. C. Kraft
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investigates the molecular machinery of autophagy, the cellular waste disposal system.
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Prof. Dr. C. Meisinger
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Investigates various topics of mitochondrial biogenesis and function in health and disease with a focus on signalling processes, protein transport mechanisms and organellar and suborganellar proteomics.
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Prof. Dr. M. Müller
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studies the mechanism of transport of proteins across and insertion into membranes.
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Prof. Dr. N. Wiedemann
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characterizes sorting of proteins in the mitochondrial outer membrane and essential mitochondrial proteins.
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PD Dr. T. Becker
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investigates the sorting and assembly machinery of the mitochondrial outer membrane.
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Dr. F. Edlich
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investigates mitochondrial apoptosis regulation by conformational changes in Bcl-2 proteins.
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Dr. H. Rampelt
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investigates protein complexes that control the architecture of the inner mitochondrial membrane.
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Dr. N. Vögtle
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investigates the role of the mitochondrial presequence proteases under physiological and pathophysiological conditions.
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Prof. (em.) Dr. R. Brandsch
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investigates two topics:
* the biogenesis of covalently flavinylated enzymes and their role as autoantigens in humans,
* the regulation of expression and the function of molybdopterin cofactor biosynthetic enzymes on catabolic plasmids.
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Prof. (em.) Dr. K. Decker
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studies the 3D-structure of a bacterial flavoprotein.
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Prof. (em.) Dr. P.C. Heinrich
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Mechanisms and regulation of signal transduction via the JAK-STAT pathway mediated by inflammatory cytokines