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Publications

Horten P, Song K, Garlich J, Hardt R, Colina-Tenorio L, Horvath SE, Schulte U, Fakler B, van der Laan M, Becker T, Stuart RA, Pfanner N, Rampelt H (2024) Identification of MIMAS, a multifunctional mega-assembly integrating metabolic and respiratory biogenesis factors of mitochondria. Cell Rep 43, 113772.

Zerbes RM, Colina-Tenorio L, Bohnert M, Peikert CD, von der Malsburg K, Mehnert CS, Perschil I, Klar R, van der Klei I, Oeljeklaus S, Warscheid B, Rampelt H, van der Laan M (2024) Coordination of cytochrome bc1 complex assembly at MICOS. bioRxiv, doi: 10.1101/2024.02.22.580370

Horten P, Rampelt H (2024) Roles of the F1Fo-ATP synthase and MICOS in mitochondrial membrane organization. In A Reichert (Ed.), The dynamic nature of mitochondria (pp. 3-23). CRC Press.

Schulte U, den Brave F, Haupt A, Gupta A, Song J, et al. (2023) Mitochondrial complexome reveals quality-control pathways of protein import. Nature 614; 153-159.

Rampelt H, Wollweber F, Licheva M, de Boer R, Perschil I, Steidle L, Becker T, Bohnert M, van der Klei I, Kraft C, van der Laan M, Pfanner N. (2022) Dual role of Mic10 in mitochondrial cristae organization and ATP synthase-linked metabolic adaptation and respiratory growth. Cell Rep. 38, 110290.

Rampelt H, Pfanner, N. (2021) Morpholinos meet mitochondria: Targeting organellar gene expression. Cell 184: 5693-5695.

Horten P, Colina-Tenorio L, Rampelt H. (2020) Biogenesis of mitochondrial metabolite carriers. Biomolecules 10: 1008.

Colina-Tenorio L, Horten P, Pfanner N, Rampelt H. (2020) Shaping the mitochondrial inner membrane in health and disease. J. Intern. Med. 287: 645-664.

Rampelt H, Sucec I, Bersch B, Horten P, Perschil I, Martinou JC, van der Laan M, Wiedemann N, Schanda P, Pfanner N. (2020) The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments. BMC Biol. 18: 2.

Rampelt H, Wollweber F, Gerke C, de Boer R, van der Klei IJ, Bohnert M, Pfanner N, van der Laan M (2018) Assembly of the mitochondrial cristae organizer Mic10 is regulated by Mic26-Mic27 antagonism and cardiolipin. J. Mol. Biol. 430: 1883-1890.

Rampelt H, van der Laan M (2017) The yin and yang of mitochondrial architecture – interplay of MICOS and F1Fo-ATP synthase in cristae formation. Microb. Cell 4: 236-239.

Ellenrieder L, Rampelt H, Becker T (2017) Connection of protein transport and organelle contact sites in mitochondria. J. Mol. Biol. 429: 2148-2160.

Hessenberger M, Zerbes RM, Rampelt H, Kunz S, Xavier AH, Purfürst B, Lilie H, Pfanner N, van der Laan M, Daumke O (2017) Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions. Nat. Commun. 8: 15258.

Rampelt H, Bohnert M, Zerbes RM, Horvath SE, Warscheid B, Pfanner N, van der Laan M (2017) Mic10, a core subunit of the mitochondrial contact site and cristae organizing system, interacts with the dimeric F1Fo-ATP synthase. J. Mol. Biol. 429: 1162-1170.

Rampelt H, Zerbes RM, van der Laan M, Pfanner N (2017) Role of the mitochondrial contact site and cristae organizing system in membrane architecture and dynamics. Biochim. Biophys. Acta 1864: 737-746.

Rampelt H, Pfanner N (2016) Coordination of two genomes by mitochondrial translational plasticity. Cell 167: 308-310.

Bohnert M, Zerbes RM, Davies KM, Mühleip AW, Rampelt H, Horvath SE, Boenke T, Kram A, Perschil I, Veenhuis M, Kühlbrandt W, van der Klei IJ, Pfanner N, van der Laan M (2015) Central role of Mic10 in the mitochondrial contact site and cristae organizing system. Cell Metab. 21: 745-755.

Rampelt H, van der Laan M (2015) Metabolic remodeling: a pyruvate transport affair. EMBO J. 34: 835-837.

Horvath SE, Rampelt H, Oeljeklaus S, Warscheid B, van der Laan M, Pfanner N (2015) Role of membrane contact sites in protein import into mitochondria. Protein Sci. 24: 277-297.

Mehnert CS, Rampelt H, Gebert M, Oeljeklaus S, Schrempp SG, Kochbeck L, Guiard B, Warscheid B, van der Laan M (2014) The mitochondrial ADP/ATP carrier associates with the inner membrane presequence translocase in a stoichiometric manner. J. Biol. Chem. 289: 27352-27362.

Rampelt H, Kirstein-Miles J, Nillegoda NB, Chi K, Scholz SR, Morimoto RI, Bukau B (2012) Metazoan Hsp70 machines use Hsp110 to power protein disaggregation.

EMBO J. 31: 4221-4235.

Rampelt H, Mayer MP, Bukau B (2011) Nucleotide Exchange Factors for Hsp70 Chaperones. Methods Mol. Biol. 787: 83-91.

Andréasson C, Rampelt H, Fiaux J, Druffel-Augustin S, Bukau B (2010) The endoplasmic reticulum Grp170 acts as a nucleotide exchange factor of Hsp70 via a mechanism similar to that of the cytosolic Hsp110. J. Biol. Chem. 285: 12445-12453.

Andréasson C, Fiaux J, Rampelt H, Druffel-Augustin S, Bukau B (2008) Insights into the structural dynamics of the Hsp110-Hsp70 interaction reveal the mechanism for nucleotide exchange activity. Proc. Natl. Acad. Sci. U S A 105: 16519-16524.

Andréasson C, Fiaux J, Rampelt H, Mayer MP, Bukau B (2008) Hsp110 is a Nucleotide-activated Exchange Factor for Hsp70. J. Biol. Chem. 283: 8877-8884.

Sadlish H, Rampelt H, Shorter J, Wegrzyn RD, Andréasson C, Lindquist S, Bukau B (2008) Hsp110 chaperones regulate prion formation and propagation in S. cerevisiae by two discrete activities. PLoS ONE 3: e1763 (2008). doi:10.1371/journal.pone.0001763.

Kwon C, Neu C, Pajonk S, Yun HS, Lipka U, Humphry M, Bau S, Straus M, Kwaaitaal M, Rampelt H, El Kasmi F, Jürgens G, Parker J, Panstruga R, Lipka V, Schulze-Lefert P (2008) Co-option of a default secretory pathway for plant immune responses. Nature 451: 835-840.