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Publications

 

Selected Publications

 
Tropschug, M., Barthelmess, I.B. und Neupert, W. (1989) "Sensitivity to cyclosporin A is mediated by cyclophilin (peptidyl-prolyl cis-trans isomerase) in Neurospora crassa and Saccharomyces cerevisiae", Nature 342, 953-955
 
Tropschug, M., Wachter, E., Mayer, S., Schönbrunner, E.R. und Schmid, F.X. (1990) "Isolation and sequence of an FK506-binding protein from N. crassa which catalyses protein folding", Nature 346, 674-677
 
Schönbrunner, E.R., Mayer, S., Tropschug, M., Fischer, G., Takahashi, N. und Schmid, F.X. (1991) "Catalysis of protein folding by cyclophilins from different species", J. Biol. Chem. 266, 3630-3635
 
Tropschug, M. und Hofmann, R. (1991) "FK506 and protein kinase C", Nature 351, 195
 
Barthelmess, I.B. und Tropschug, M. (1993) "FK506-binding protein of Neurospora crassa (NcFKBP) mediates sensitivity to the immunosuppressant FK506; resistant mutants identify two loci", Curr. Genet. 23, 54-58
 
Rassow, J., Mohrs, K., Koidl, S., Barthelmess, I.B., Pfanner, N. und Tropschug, M. (1995) "Cyclophilin 20 is involved in mitochondrial protein folding in cooperation with molecular chaperones Hsp70 and Hsp60", Mol. Cell. Biol. 15, 2654-2662
 
Kruse, M., Brunke, M., Escher, A., Szalay, A.A., Tropschug, M. und Zimmermann, R. (1995) "Enzyme assembly after de novo synthesis in rabbit reticulocyte lysate involves molecular chaperones and immunophilins", J. Biol. Chem. 270, 2588-2594
 
Mi, H., Kops, O., Zimmermann, E., Jäschke, A. und Tropschug, M. (1996) "A nuclear RNA-binding cyclophilin in human T cells", FEBS Lett. 398, 201-205
 
Prokisch, H., Yarden, O., Dieminger, M., Tropschug, M. und Barthelmess, I.B. (1997) "Impairement of calcineurin function in Neurospora crassa reveals its essential role in hyphal growth, morphology and maintenance of the apical Ca2+-gradient", Mol. Gen. Genet. 256, 104-114
 
von Ahsen, O., Tropschug, M., Pfanner, N. und Rassow, J.(1997) "The chaperonin-cycle cannot substitute for prolyl isomerase activity, but GroEl alone promotes productive folding of a cyclophilin-sensitive substrate to a cyclophilin-resistant form", EMBO J. 16, 4568-4578
 
Jäschke, A., Mi, H. und Tropschug, M. (1998) "Human T cell cyclophilin18 binds to thiol-specific antioxidant protein Aop1 and stimulates its activity", J. Mol. Biol. 277, 763-769
 
Kops, O., Eckerskorn, C., Hottenrott, S., Fischer, G., Mi, H. und Tropschug, M. (1998) "Ssp1, a site specific parvulin homolog from Neurospora crassa active in protein folding", J. Biol. Chem. 273, 31971-31976
 
Solscheid, B. und Tropschug, M. (2000) "A novel type of FKBP in the secretory pathway of Neurospora crassa", FEBS Lett. 480, 118-122
 
Fair, K., Anderson, M., Bulanova, E., Mi, H., Tropschug, M., und Diaz, M.O. (2001) "Protein Interactions of the MLL PHD Fingers Modulate MLL Target Gene Regulation in Human Cells" Mol. Cell. Biol.  21, 3589-3597.
 
Brustovetsky, N., Tropschug, M., Heimpel, S., Heidkämper, D. und Klingenberg, M. (2002) "A large Ca2+-dependent channel formed by recombinant ADP/ATP carrier from Neurospora crassa resembles the mitochondrial permeability transition pore", Biochemistry 41, 11804-11811
 
Faou, P. und Tropschug, M. (2003) "A novel binding protein for a member of CyP40-type cyclophilins: N. crassa CyPBP37, a growth and thiamine regulated protein homolog to yeast Thi4p", J. Mol. Biol. 333, 831-844.
 
Faou, P. und Tropschug, M. (2004) "Neurospora crassa CyPBP37: a cytosolic stress protein that is able to replace yeast Thi4p function in the synthesis of vitamin B1" J. Mol. Biol. 344, 1147-1157.
 
Tremmel, D. und Tropschug, M. (2007) "Neurospora crassa FKBP22 is a Novel ER Chaperone and Functionally Cooperates with BiP" J. Mol. Biol. , 369, 55-68
 
Tremmel, D., Duarte, M., Videira, A. und Tropschug, M. (2007) "FKBP22 is part of chaperone/folding catalyst complexes in the endoplasmic reticulum of N. crassa" FEBS Lett., 581, 2036-2040
 
Pinto, D., Duarte, M., Soares, S., Tropschug, M. und Videira, A. (2008) "Identification of all FK506-binding proteins from Neurospora crassa." Fungal Genet. and Biol. 45, 1600-1607.
 

Reviews:

 
Tropschug, M. (1997a) "N. crassa cyclophilins" in: Guidebook to Molecular Chaperones and Protein Folding Catalysts; M.-J. Gething, ed. (Oxford: Sambrook & Tooze at Oxford University Press), 382-384
 
Tropschug, M. (1997b) "N. crassa FKBPs" in: Guidebook to Molecular Chaperones and Protein Folding Catalysts; M.-J. Gething, ed. (Oxford: Sambrook & Tooze at Oxford University Press), 416-417

 

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