How is the interaction of RPBs with the ribosome regulated in time and space and
how do RPBs contribute to the biogenesis of newly synthesized proteins ?
What are the in vivo roles of the chaperone Ssb on the ribosome and in the cytosol ?
How do mammalian ribosome-bound chaperones work and what additional functions have
they aquired in higher eukaryotes ?
How do specific nascent chains inside and outside of the ribosomal tunnel affect
the interplay with RPBs?