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Selected Publications

Lopez, J., Bessou, M., Riley, J.S., Giampazolias, E., Todt, F., Rochegüe, T., Oberst, A., Green, D.R., Edlich, F., Ichim, G., Tait, S.W.G. (2016). Mito-priming as a novel method of engineered Bcl-2 addiction. Nat. Comm., 7:10538

Schleicher, R., Reichenbach, F., Kraft, P., Kumar, A., Lescan, M., Todt, F., Göbel, K., Hilgendorf, I., Geisler, T., Bauer, A., Olbrich, M., Schaller, M., Wesselborg, S., O'Reilly, L., Meuth, S., Schulze-Osthoff, K., Gawaz, M., Li, X., Kleinschnitz, C., Edlich, F., Langer, H.F. (2015) Platelets induce apoptosis via membrane-bound FasL. Blood 126, 1483-93.

Todt, F., Cakir, Z., Reichenbach, F., Emschermann, F., Lauterwasser, J., Kaiser, A., Ichim, G., Tait, S.W.G., Frank, S., Langer, H.F. and Edlich, F. (2015). Differential retrotranslocation of mitochondrial Bax and Bak. EMBO J. 34, 67-80

Todt, F., Cakir, Z., Reichenbach, F., Youle, R.J., Edlich, F. (2013) The C-terminal helix of Bcl-x(L) mediates Bax retrotranslocation from the mitochondria. Cell Death Differ, 20, 333-42

Ma, J., Edlich, F., Bermejo, G.A., Norris, K.L., Youle, R.J., Tjandra, N. (2012) Structural Mechanism of Bax Inhibition by Cytomegalovirus Protein vMIA. Proc Natl Acad Sci USA, 109, 20901-6

Edlich, F., Banerjee, S., Suzuki, M., Cleland, M.M., Arnoult, D., Wang, C., Neutzner, A., Tjandra, N., Youle, R.J. (2011) Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol. Cell 145, 104-16.

Hoppins, S., Edlich, F., Cleland, M.M., Banerjee, S., McCaffery, J.M., Youle, R.J., Nunnari, J. (2011) The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes. Mol Cell 41, 150-60.

Jarczowski, F., Jahreis, G., Erdmann, F., Schierhorn, A., Fischer, G., Edlich, F. (2009). FKBP36 is an inherent multifunctional glyceraldehyde-3-phosphate dehydrogenase inhibitor. J Biol Chem 284, 766-73.

Jarczowski, F., Fischer G., Edlich, F. (2008). FKBP36 forms complexes with clathrin and Hsp72 in spermatocytes. Biochemistry 47, 6946-6952.

Edlich, F., Maestre-Martinez, M., Jarczowski, F., Weiwad, M., Moutty, M.-C., Malesevic, M., Jahreis, G., Fischer G., Lücke, C. (2007). A novel calmodulin-Ca2+ target recognition activates the Bcl-2 regulator FKBP38. J Biol Chem 282, 36496-36504.

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